Design
(PUBLISHED)
March 12, 2025
(WRITER)
Dantes
In recent years, more and more scientific research is pointing toward a common issue behind aging, chronic diseases, and even weakened immunity: DNA damage.
But what causes our DNA to deteriorate? Is this the price of modern life, or is it part of a deeper evolutionary story?
Believe it or not, the human body once had the ability to synthesize vitamin C (ascorbic acid) on its own.
Just like cats, dogs, rats, and many other mammals still do today, early humans also had a working version of the GULO gene (gulonolactone oxidase). This gene is responsible for producing the enzyme needed for the final step of vitamin C synthesis.
However, over millions of years, this gene became inactive in humans, some primates, and guinea pigs. As a result, we lost the ability to produce vitamin C naturally and are now entirely dependent on dietary sources such as fruits and vegetables.
The loss of this vital function is a compelling example of how our DNA has changed—and in some cases, deteriorated—over time.
DNA damage can be caused by a variety of factors, broadly categorized into endogenous (internal) and exogenous (external) sources.
When DNA is damaged or its code is altered, the instructions for making proteins can become scrambled. This may lead to:
In essence, even a small change in DNA can cause a ripple effect that impacts the entire body.
While humans and some other species have lost the ability to make vitamin C, many animals still retain this life-saving feature:
These animals are naturally protected against vitamin C deficiency, whereas humans must consume it daily.
This fact shows how evolutionary DNA damage can lead to significant biological consequences.
While it’s impossible to stop DNA degradation entirely, there are proven ways to slow it down and support DNA repair mechanisms.
Our DNA isn’t unbreakable. We’ve lost functions like vitamin C synthesis through evolution, and we’re still vulnerable to modern environmental threats.
But the good news is: we can influence how well our DNA holds up.
A healthy lifestyle, nutrient-rich diet, and conscious habits can support our genetic material and delay deterioration.
Understanding how and why our DNA breaks down is the first step toward protecting it—and ourselves—for generations to come.